Dr Shane Ohline
Nerve cells born in adulthood
This image shows fully matured brain cells (neurons), in magenta, within the brain which developed during adulthood from neuronal stem cells (NSCs). The branching coming off the main body of the neuron demonstrates that these cells are participating and contributing to the circuitry of the brain. This suggests that neurons born in adulthood from NSCs continue to grow and develop throughout our lives, and are vital to the maintenance of a functioning brain.
Dr Ohline studies the mechanisms involved in learning and memory and uses these cells to determine the functional changes which occur as a result of ageing. This has significant implications when we consider neurological conditions such as Alzheimer’s disease, the most common form of dementia, which tend to be associated with ageing and impact one’s ability to learn and retain new information. By studying these cells, this research team hopes to enhance the functioning of these adult-born neurons, by both preserving, and encouraging them to participate in learning and memory, leading to possible therapies for Alzheimer’s disease.